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Did You Know?

You may already be familiar with the raised, scaly red patches of psoriasis,1,2 but did you know that psoriasis can affect more than skin? Psoriatic disease can affect different areas of the body, including the skin, nails, palms and soles, the scalp and the skeletal system (including the spine and joints).1,3,9

Psoriasis is more than a skin condition.1,2

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WHAT IS PSORIATIC DISEASE?

Psoriatic Disease (PsD) is a collective term for multiple manifestations of psoriasis.1,4

PsD is an AUTOIMMUNE condition, which means the body’s immune system is overactive and targets the body’s own healthy tissue as if it is fighting a foreign infection.3,5,6 The body’s response to the attack is inflammation or swelling.6,7

PsD is also SYSTEMIC.3 This means it can affect different areas of the body including joints, which become swollen and painful.3,6 This is called psoriatic arthritis and if left untreated, PsA can cause severe joint damage making it harder for you to do the things you once found easy – like getting out of bed, climbing stairs, or using your hands.7,8

At its worst, it can lead to permanent disability if left untreated.7,8

FormsOfPSD
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Psoriasis usually appears on the skin first, sometimes years before the symptoms of psoriatic arthritis begin but, more rarely, psoriatic arthritis can exist on its own or before skin symptoms.8

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References:
1. Gladman DD. F1000Research. 2016; 5:2670. 2. Johnson-Huang LM, et al. Disease Models & Mechanisms. 2012; 5:423–433 3. Chimenti MS et al. Autoimmunity Reviews. 2019; 18:565–575. 4. Pollock RA, et al. Arthritis Care & Research. 2015; 67:1586–1590. 5. Mitra A, et al. Actas Dermosifiliogr. 2014 105:21–33. 6. Cantrell W, et al. Prac Derm. 2018; 2018:38–45. 7. Feldman SR, et al. Dermatology Online Journal. 2018; 24(10):1. 8. Lloyd P et al. Arthritis. 2012; 2012:176298. 9. Wilson FC, et al. Arthritis Rheum. 2009; 61:233–239.