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Fusing? Let's Fight It!

Ankylosing Spondylitis originates from the Greek words ‘ankylos’ and ‘spondylos’ which literally mean fused bones.[1] It is a progressive disease, which may lead to restrictions in mobility and ultimately loss in function.[2]

What does disease progression mean?

Simply put, disease progression in Ankylosing Spondylitis means the disease could worsen over time. Ankylosing Spondylitis causes inflammation, which damages the spinal bones. The damaged bones are replaced with repair tissue, on which tiny new bones are formed. These newly formed abnormal bones use up the space in between themselves, ultimately resulting in fusion or 'bamboo spine'![3]


What does this imply?

Spinal damage and fusion can be potentially disabling.[3] Fusion of the spinal bones may translate into:[3]

  • Inability to move freely

  • Loss of function

  • Disability

  • Pain

  • Fatigue

Since Ankylosing Spondylitis affects people in their 20's or 30's, neglect or improper treatment can result in a lifetime of immobility.[3]


  1. Defining Anklyosing Spondylitis. Merriam Webster dictionary. Available [Online] at: Accessed on 20th Sep 2021

  2. Gran JT, et al. British Journal of Rheumatology 1997;36:766-771

  3. Sieper J, et al. Ann Rheum Dis 2002;61(Suppl III):iii8–iii18

  4. Poddubnyy D, Siper J. Curr Rheumatol Rep 2017; 19: 55

Disclaimer: This material is not meant to replace professional advice from HCPs. Please consult your doctors/physiotherapist if you have any questions or before undertaking any physical activities.